Rabbit Secondary Antibodies
ABclonal Technology 647 Rabbit anti-Human CD84
This gene encodes a membrane glycoprotein that is a member of the signaling lymphocyte activation molecule (SLAM) family This family forms a subset of the larger CD2 cell-surface receptor Ig superfamily The encoded protein is a homophilic adhesion molecule that is expressed in numerous immune cells types and is involved in regulating receptor-mediated signaling in those cells Alternate splicing results in multiple transcript variants
ABclonal Technology PE Rabbit anti-Human CR2/CD21
This gene encodes a membrane protein which functions as a receptor for Epstein-Barr virus (EBV) binding on B and T lymphocytes Genetic variations in this gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9) Alternatively spliced transcript variants encoding different isoforms have been found for this gene
ABclonal Technology 647 Rabbit anti-Human CD94
Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation Several genes of the C-type lectin superfamily including members of the NKG2 family are expressed by NK cells and may be involved in the regulation of NK cell function KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus Three transcript variants encoding two different isoforms have been found for this gene
ABclonal Technology 488 Rabbit anti-Human PLZF
This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus This protein is located in the nucleus is involved in cell cycle progression and interacts with a histone deacetylase Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL) Alternate transcriptional splice variants have been characterized
ABclonal Technology 488 Rabbit anti-Human CD98
This gene is a member of the solute carrier family and encodes a cell surface transmembrane protein The protein exists as the heavy chain of a heterodimer covalently bound through di-sulfide bonds to one of several possible light chains The encoded transporter plays a role in regulation of intracellular calcium levels and transports L-type amino acids Alternatively spliced transcript variants encoding different isoforms have been characterized
ABclonal Technology 647 Rabbit anti-Human CD172b
The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family and also belongs to the immunoglobulin superfamily SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes This protein was found to interact with TYROBP DAP12 a protein bearing immunoreceptor tyrosine-based activation motifs This protein was also reported to participate in the recruitment of tyrosine kinase SYK Multiple transcript variants encoding different isoforms have been found for this gene
Vector Laboratories IHC‑plus Polyclonal Rabbit anti‑Human IL13RA1 / IL13R Alpha 1 Antibody Lys401 IHC IF WB - 50ul
IHC‑plus Polyclonal Rabbit anti‑Human IL13RA1 / IL13R Alpha 1 Antibody Lys401 IHC IF WB - 50ul
ABclonal Technology 488 Rabbit anti-Human SIGLEC9
Predicted to enable monosaccharide binding activity and sialic acid binding activity Predicted to be involved in cell adhesion Predicted to act upstream of or within negative regulation of inflammatory response and negative regulation of phagocytosis engulfment Predicted to be located in external side of plasma membrane Predicted to be active in plasma membrane
ABclonal Technology PE Rabbit anti-Human CD1B mAb
This gene encodes a member of the CD1 family of transmembrane glycoproteins which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells The human genome contains five CD1 family genes organized in a cluster on chromosome 1 The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail and requires vesicular acidification to bind lipid antigens
ABclonal Technology 647 Rabbit anti-Human CD300a
This gene encodes a member of the CD300 glycoprotein family of cell surface proteins found on leukocytes involved in immune response signaling pathways This gene is located on chromosome 17 in a cluster with all but one of the other family members Multiple transcript variants encoding different isoforms have been found for this gene
Jackson Immuno Research Labs Alexa Fluor 647-AffiniPure Rabbit Anti-Human IgA+IgG+IgM (H+L)
Alexa Fluor 647-AffiniPure Rabbit Anti-Human IgA+IgG+IgM (H+L)
ABclonal Technology APC Rabbit anti-Human CD38 mAb
The protein encoded by this gene is a non-lineage-restricted type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5 -diphosphate-ribose an intracellular calcium ion mobilizing messenger The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein This protein has an N-terminal cytoplasmic tail a single membrane-spanning domain and a C-terminal extracellular region with four N-glycosylation sites Crystal structure analysis demonstrates that the functional molecule is a dimer with the central portion containing the catalytic site It is used as a prognostic marker for patients with chronic lymphocytic leukemia Alternative splicing results in multiple transcript variants
ABclonal Technology PE Rabbit anti-Human TLR3 mAb
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity TLRs are highly conserved from Drosophila to humans and share structural and functional similarities They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents and mediate the production of cytokines necessary for the development of effective immunity The various TLRs exhibit different patterns of expression This receptor is most abundantly expressed in placenta and pancreas and is restricted to the dendritic subpopulation of the leukocytes It recognizes dsRNA associated with viral infection and induces the activation of NF-kappaB and the production of type I interferons It thus plays a role in host defense against multiple viruses